東北大学病院 腫瘍内科｜東北大学大学院医学系研究科・医学部

研究室紹介

研究業績

英文論文 2012年度

  1. Antelo, M.，Balaguer, F.，Shia, J.，Shen, Y.，Hur, K.，Moreira, L.，Cuatrecasas, M.，Bujanda, L.，Giraldez, M. D.，Takahashi, M.，Cabanne, A.，Barugel, M. E.，Arnold, M.，Roca, E. L.，Andreu, M.，Castellvi-Bel, S.，Llor, X.，Jover, R.，Castells, A.，Boland, C. R.，Goel, A. A high degree of LINE-1 hypomethylation is a unique feature of early-onset colorectal cancer. PLoS One 7: e45357 (2012)
  2. Kato, S.，Andoh, H.，Gamoh, M.，Yamaguchi, T.，Murakawa, Y.，Shimodaira, H.，Takahashi, S.，Mori, T.，Ohori, H.，Maeda, S.，Suzuki, T.，Kato, S.，Akiyama, S.，Sasaki, Y.，Yoshioka, T.，Ishioka, C.，Tohoku Clinical Oncology, R.，Education. Safety verification trials of mFOLFIRI and sequential IRIS + bevacizumab as first- or second-line therapies for metastatic colorectal cancer in Japanese patients. Oncology 83: 101-7 (2012)
  3. Shirota, H.，Klinman, D. M. Effect of CpG ODN on monocytic myeloid derived suppressor cells. Oncoimmunology 1: 780-782 (2012)
  4. Takahashi, M.，Cuatrecasas, M.，Balaguer, F.，Hur, K.，Toiyama, Y.，Castells, A.，Boland, C. R.，Goel, A. The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer. PLoS One 7: e46684 (2012)
  5. Tsushima, T.，Taguri, M.，Honma, Y.，Takahashi, H.，Ueda, S.，Nishina, T.，Kawai, H.，Kato, S.，Suenaga, M.，Tamura, F.，Morita, S.，Boku, N. Multicenter retrospective study of 132 patients with unresectable small bowel adenocarcinoma treated with chemotherapy. Oncologist 17: 1163-70 (2012)
  6. Watanabe, M.，Baba, H.，Ishioka, C.，Nishimura, Y.，Muto, M. Recent advances in diagnosis and treatment for malignancies of the gastrointestinal tract. Digestion 85: 95-8 (2012)
  7. Shiono, M.，Shimodaira, H.，Watanabe, M.，Takase, K.，Ito, K.，Miura, K.，Takami, Y.，Akiyama, S.，Kakudo, Y.，Takahashi, S.，Takahashi, M.，Ishioka, C. Multidisciplinary approach to a case of Lynch syndrome with colorectal, ovarian, and metastatic liver carcinomas. International Cancer Conference Journal 1: 125-137 (2012)
  8. Saiki, Y.，Yoshino, Y.，Fujimura, H.，Manabe, T.，Kudo, Y.，Shimada, M.，Mano, N.，Nakano, T.，Lee, Y.，Shimizu, S.，Oba, S.，Fujiwara, S.，Shimizu, H.，Chen, N.，Nezhad, Z. K.，Jin, G.，Fukushige, S.，Sunamura, M.，Ishida, M.，Motoi, F.，Egawa, S.，Unno, M.，Horii, A. DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells. Biochem Biophys Res Commun 421: 98-104 (2012)
  9. Shibahara, I.，Sonoda, Y.，Kanamori, M.，Saito, R.，Yamashita, Y.，Kumabe, T.，Watanabe, M.，Suzuki, H.，Kato, S.，Ishioka, C.，Tominaga, T. IDH1/2 gene status defines the prognosis and molecular profiles in patients with grade III gliomas. Int J Clin Oncol 17: 551-61 (2012)
  10. Takahashi, M.，Furukawa, Y.，Shimodaira, H.，Sakayori, M.，Moriya, T.，Moriya, Y.，Nakamura, Y.，Ishioka, C. Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome. Fam Cancer 11: 559-64 (2012)
  11. Takahashi, M.，Sung, B.，Shen, Y.，Hur, K.，Link, A.，Boland, C. R.，Aggarwal, B. B.，Goel, A. Boswellic acid exerts antitumor effects in colorectal cancer cells by modulating expression of the let-7 and miR-200 microRNA family. Carcinogenesis 33: 2441-9 (2012)
  12. Sekine, H.，Chen, N.，Sato, K.，Saiki, Y.，Yoshino, Y.，Umetsu, Y.，Jin, G.，Nagase, H.，Gu, Z.，Fukushige, S.，Sunamura, M.，Horii, A. S100A4, frequently overexpressed in various human cancers, accelerates cell motility in pancreatic cancer cells. Biochem Biophys Res Commun 429: 214-9 (2012)
  13. Kais, Z.，Chiba, N.，Ishioka, C.，Parvin, J. D. Functional differences among BRCA1 missense mutations in the control of centrosome duplication. Oncogene 31: 799-804 (2012)
  14. Garcia, M.，Choi, C.，Kim, H. R.，Daoud, Y.，Toiyama, Y.，Takahashi, M.，Goel, A.，Boland, C. R.，Koi, M. Association between recurrent metastasis from stage II and III primary colorectal tumors and moderate microsatellite instability. Gastroenterology 143: 48-50 e1 (2012)
  15. Nomizu, T.，Sakuma, T.，Yamada, M.，Matsuzaki, M.，Katagata, N.，Watanabe, F.，Nihei, M.，Ishioka, C.，Takenoshita, S.，Abe, R. Three cases of kindred with familial breast cancer in which carrier detection by BRCA gene testing was performed on family members. Breast Cancer 19: 270-4 (2012)
  16. Shen, Y.，Takahashi, M.，Byun, H. M.，Link, A.，Sharma, N.，Balaguer, F.，Leung, H. C.，Boland, C. R.，Goel, A. Boswellic acid induces epigenetic alterations by modulating DNA methylation in colorectal cancer cells. Cancer Biol Ther 13: 542-52 (2012)
  17. Yasuda, K.，Kato, S.，Sakamoto, Y.，Watanabe, G.，Mashiko, S.，Sato, A.，Kakudo, Y.，Ishioka, C. Induction of apoptosis by cytoplasmically localized wild-type p53 and the S121F mutant super p53. Oncol Lett 3: 978-982 (2012)
  18. Saijo, K.，Katoh, T.，Shimodaira, H.，Oda, A.，Takahashi, O.，Ishioka, C. Romidepsin (FK228) and its analogs directly inhibit phosphatidylinositol 3-kinase activity and potently induce apoptosis as histone deacetylase/phosphatidylinositol 3-kinase dual inhibitors. Cancer Sci 103: 1994-2001 (2012)